Methylated B Vitamins: What Roles Do They Play For The Body?

Methylated B vitamins can help in so many ways.

Methylated B Vitamins are the vitamins that have undergone DNA methylation. In actuality, several B vitamins contribute to both methylation and detoxification. Among these B vitamins are B12 and folate. Every vitamin plays an essential role inside the body. As for B12, a lack of it can lead to developing gum problems. A dentist (follow this link) can also help work out your B12 and other vitamin deficiencies to address the oral problem as well.


What is Methylation?

Methylation is a biochemical process that involves transferring four atoms from one component to another. It involves one carbon atom and three hydrogen atoms (CH3). SAM-e (S-adenosylmethionine or SAMe) is the methyl donor that provides the CH3 to the body. Furthermore, it gives away its methyl group to the body’s other substances.

Meanwhile, this process has an essential role inside the body. It regulates stress response, brain chemistry, immune system, and many more. Generally speaking, we all know how complex the body is. Not everyone may know about it as precisely as those who study human anatomy. But, we can all believe that the body has its functions beyond what the eyes can see.


Symptoms Requiring Methylation Support

The following signifies that you may need methylation support.

  • A man feeling so tired at work may be experiencing imbalanced methylation cycle.Ongoing fatigue
  • Family history of cardiovascular disease
  • Family history of anxiety and depression
  • Poor mood
  • Concentration difficulties
  • Chronic constipation
  • Inflammation
  • High homocysteine and liver enzymes
  • Low vitamin B12 and folate
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Any of these signs require attention. Addressing them as soon as possible can help you save your health from any related diseases.


Vitamin B-complex

This vitamin carries eight of the B vitamins. That includes the following.

  • Thiamin or B1
  • Riboflavin or vitamin B2
  • Niacin or B3
  • Pantothenic acid or B5
  • Pyridoxine or vitamin B6
  • Biotin or B7
  • Folate or B9
  • Cobalamin or vitamin B12

Among these eight B vitamins, let’s focus on the last two of them: vitamin B12 and folate. What roles do these two B vitamins play for our health? Let’s know them better.


Folate, is it the Same as Folic Acid?

Folate is a b-complex vitamin that you can get from fruits and vegetables. Meanwhile, folic acid is a synthetic form of folate made from bacteria. You can find folic acid in dietary supplements and some processed foods.

The folate vitamin and folic acid are both essential to the body. It needs these components for cell division and growth. Furthermore, these two offer several benefits if they have a sufficient amount of it inside their system.

Here are some benefits that you can gain from maintaining these two inside your body sufficiently.

  • It lowers the risks of developing certain cancers and cardiovascular diseases.
  • Additionally, folic acid lowers homocysteine levels in the blood. Homocysteine is the protein that can lead to developing cardiovascular diseases when at high levels.


Vitamin B12

The other name for B12 is cobalamin, and it is water-soluble. Additionally, it is a crucial vitamin B. It helps maintain nerve tissue, brain function, and red blood cells production. Moreover, the lack of it can lead to neurological difficulties and anemia.

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This vitamin is available in various resources, such as beef, pork, ham, nutritional yeast products, and many more. Here are some more benefits that you can gain from this B vitamin.

  • It maintains the regular activity of the brain and the nervous system (NS).
  • Additionally, it is essential to the synthesis of fatty acids and energy production.
  • It helps the body’s absorption of folic acid.
  • Furthermore, it helps red blood cells multiplication.


The Importance of Methylation Cycle

Methylation is an essential process to help us function mentally and physically. It involves a methyl group molecule added to another substance, such as DNA or protein. In effect, the receiving component will work.

DNA consists of our genes that hone who we are. In this case, methylation is essential because it helps our DNA work properly. Methylation also serves as the link to the environment, nutrition, and disease. Furthermore, imbalanced methylation causes mood and NS disorders, allergies, and the aging process.

The methylation cycle will take place effectively if there is enough 5 MTHF, an active form of folate. Meanwhile, a genetic test is available to confirm if there is a problem with the methylation cycle. The test involves checking a specific enzyme, which is the methylenetetrahydrofolate reductase (MTHFR gene).

The genetic test helps prevent methylation disorders. Besides that, many healthy foods are available to improve the methylation cycle. That includes the following:

  • Avocado
  • Asparagus
  • Broccoli
  • Brussel sprouts
  • Green, leafy vegetables
  • Peas, beans, and lentils
  • Rice

Generally speaking, healthy foods help us prevent any disease from affecting our overall health.

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Note About Supplements

Supplements may or may not be necessary to an individual.A supplement is not intended to diagnose, treat, cure, or prevent any disease. The Food and Drug Administration does not have the authority to evaluate or approve supplements and vitamins, such as a B-complex supplement. In this case, the Food and Drug Administration does not secure any list of manufacturers, distributors, or any dietary supplement they sell. For this reason, it is necessary to ask medical professionals before purchasing or taking a supplement. There could be reactions in the body that signify conflict with the medicine a person is taking or their medical condition. Supplementation serves as support only for the potential lacking vitamins, including folate and vitamin B12.


Thoughts to Ponder

If you think you have issues with your methylation cycle, ask your physician about it. Moreover, they can provide you with all the information you need to improve your quality of life. That may include the nutrients you need, supplements, and other health tips. Besides, a product may have potential side effects you need to be aware of as well. Health is wealth. It is necessary to do our best to maintain it excellently.



What is Methylation and Why Should You Care About it, Alan Miller, ND, September 03, 2018,

All about methylation and what you can do to keep yours healthy, Georgia Marrion, BHSc(Comp med) AdvDipHSc(Nat) MHumNut, November 14, 2016,


Author: b5supp

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